Home-based care programme (HBCP) for patients with COVID-19: Boon or burden during pandemic management?

Introduction and Aim: India experienced the peak of the second wave of COVID-19 during April to June 2021. Massive surge of cases resulting in shortage of beds and oxygen, home care was recommended as a strategy for management of asymptomatic/mild COVID-19 cases. The present study was undertaken to perform home visits and monitor COVID 19 patients who are a part of home-based care programme (HBCP) in Puttur taluk of Dakshina Kannada district, identification and immediate referral of patients with red flag signs/ symptoms and to identify barriers/challenges faced by health care staff in implementing the programme. Methodology: The present study was a cross-sectional study with universal sampling. It was carried out as part of a district programme for management of home isolation COVID-19 patients. The team visited the houses of COVID-19 patients and evaluated them. Result(s): A total of 112 COVID-19 patients were in home isolation during the study period in Puttur Taluk. Hypertension (29.5%) was the most common co-morbidity and nearly two-fifths (41.1%) of the study participants had one or more comorbidities. Almost two-third (63%) of the patients with comorbidities were symptomatic compared to only 29.4% of patients without any comorbidities. Of the six patients who had saturation of less than 95% five were more than 60 years of age, only one had received vaccination against COVID-19 and all had comorbidities. The HBCP had to face several challenges as the team members could not be in full PPE because of long distances between the houses and hard to reach areas. Conclusion(s): Overall, it is a helpful initiative for patients as the health services were provided at the doorstep during the time of restriction of movement. This can be an important tool in managing not only COVID pandemic but also future outbreaks that may follow.Copyright © 2023, Indian Association of Biomedical Scientists. All rights reserved.

Cost-Effectiveness Analysis of Nonpharmaceutical Interventions Combined with Inactivated Vaccination and Oral Medicine in China

Objectives: Various interventions were used to control the COVID-19 pandemic and protect population health, including vaccination, medication and nonpharmaceutical interventions (NPIs). This study aims to examine the cost-effectiveness of different combinations of NPIs (including social distancing, mask wearing, tracing-testing-isolation, mass testing, and lockdown), oral medicine (Paxlovid), and vaccination (including two-dose and three-dose vaccination) under the Delta and Omicron pandemic in China. Method(s): We constructed a Markov model using a SIRI structure with a one-week cycle length over one-year time horizon to estimate the cost-effectiveness of different combinations in China from societal perspective. Effectiveness of interventions, disease transition probabilities and costs were from published data, quality-adjusted life years (QALYs) gained and incremental cost-effectiveness ratios (ICER) and net monetary benefits were calculated for one-year time horizon. One-way and probabilistic sensitivity analyses were performed to test the robustness of the model. Scenario analysis was developed to examine different situations under the Omicron pandemic. Result(s): Under the Delta pandemic, implementing the combination of social distancing, mask wearing, mass testing and three-dose vaccination was the optimal strategy, with cost at $11165635.33 and utility of 94309.94 QALYs, and had 60% probability of being cost-effective compared with other strategies. Three-dose vaccination combinations were better than two-dose combinations. Under the Omicron pandemic, antigen testing was better than nucleic testing by avoiding cross infections;second, adding Paxlovid or lockdown to the combined intervention strategies could increase limited health outcomes at huge cost and thus were not cost-effective;last, encouraging patients to stay at home can save societal costs compared with concentrated quarantine at hospitals. Conclusion(s): Three-dose vaccination and self-quarantine of asymptomatic and mild cases can save total costs. Under the Omicron pandemic outbreak, antigen testing is a better way to control the pandemic, and adding Paxlovid or lockdown to intervention combinations is not cost-effective.Copyright © 2023

Isolated Hyoid Fracture Associated with Blunt Trauma

Trauma-related hyoid fractures are rare entities. These fractures represent only 0.002% of head and neck region fractures. Victims of hanging and strangling constitute the great majority of cases. Fractures associated with trauma are extremely rare. These fractures are difficult to diagnose and can easily be overlooked during physical examination. However, they are also important traumas since airway safety is endangered in these rare cases. We describe a case of a young male presenting with isolated neck injury associated with hitting an electric cable while riding a motorbike. Tenderness was present in the anterior neck region at physical examination, but movement was not restricted and no respiratory difficulty was determined. Isolated hyoid fracture was detected at tomography of the neck performed in the emergency department. Hyoid bone fractures should not be forgotten in patients with pain and tenderness in the anterior neck region following blunt trauma to the neck.©Copyright 2020 by Emergency Physicians Association of Turkey - Available online at www.jemcr.com.

Home quarantine during COVID-19 blunted childhood trauma-related psychiatric symptoms in Chinese college students.

Background: Childhood trauma confers risks to mental health. However, little is known about whether home quarantine (HQ) during the coronavirus disease 2019 (COVID-19) pandemic exaggerated or mitigated the effect of childhood trauma on mental health. Objective: To examine the modulating effects of prior childhood traumas on the longitudinal changes of psychiatric symptoms in college students before and after HQ during the pandemic. Methods: This was a two-wave longitudinal study on the mental health of 2,887 college students before and after HQ during the COVID-19 pandemic. The relationships between the changes in the Patient Health Questionnaire-9 (PHQ-9), Symptom Checklist-90 (SCL-90), 16-item Prodromal Questionnaire (PQ-16), Childhood Trauma Questionnaire (CTQ), and Social Support Rating Scale (SSRS) scores were analyzed. Results: The students with childhood trauma showed a significantly greater decrement in psychiatric symptoms after HQ (F = 17.21, 14.11, 18.87, and 17.42 for PHQ-9, PQ-16 objective and distress, and SCL-90, respectively). The correlation coefficients between the CTQ and these symptoms scales were significant at baseline (r = 0.42, 0.34, 0.37, and 0.39), and decreased after HQ (r = 0.17, 0.20, 0.18, and 0.19). The decrement of depressive, psychotic, and overall symptoms was positively correlated with the scores of the CTQ (r = 0.08-0.27) but negatively correlated with SSRS (r = -0.08--0.14). Multilinear regression analysis confirmed the results of the CTQ and SSRS regarding the modulation of the dynamic changes in psychiatric symptoms. A constructed structural equation model indicated that the total effects of childhood trauma on decreased psychiatric symptoms were partly mediated by lower baseline social support. Conclusion: Home quarantine during the COVID-19 pandemic could blunt the adverse effects of childhood trauma on mental health, especially for prodromal psychotic symptoms in college students. Changes in relative deprivation and social support may be mediating factors.

Risk factors associated with indoor transmission during home quarantine of COVID-19 patients.

Purpose: The study aimed to identify potential risk factors for family transmission and to provide precautionary guidelines for the general public during novel Coronavirus disease 2019 (COVID-19) waves. Methods: A retrospective cohort study with numerous COVID-19 patients recruited was conducted in Shanghai. Epidemiological data including transmission details, demographics, vaccination status, symptoms, comorbidities, antigen test, living environment, residential ventilation, disinfection and medical treatment of each participant were collected and risk factors for family transmission were determined. Results: A total of 2,334 COVID-19 patients participated. Compared with non-cohabitation infected patients, cohabitated ones were younger (p = 0.019), more commonly unvaccinated (p = 0.048) or exposed to infections (p < 0.001), and had higher rates of symptoms (p = 0.003) or shared living room (p < 0.001). Risk factors analysis showed that the 2019-nCov antigen positive (OR = 1.86, 95%CI 1.40-2.48, p < 0.001), symptoms development (OR = 1.86, 95%CI 1.34-2.58, p < 0.001), direct contact exposure (OR = 1.47, 95%CI 1.09-1.96, p = 0.010) were independent risk factors for the cohabitant transmission of COVID-19, and a separate room with a separate toilet could reduce the risk of family transmission (OR = 0.62, 95%CI 0.41-0.92, p = 0.018). Conclusion: Patients showing negative 2019-nCov antigen tests, being asymptomatic, living in a separate room with a separate toilet, or actively avoiding direct contact with cohabitants were at low risk of family transmission, and the study recommended that avoiding direct contact and residential disinfection could reduce the risk of all cohabitants within the same house being infected with COVID-19.

Severe Acute Hepatitis: An Emerging Grave Illness in Children

Acute hepatitis of unknown origin in children has been recently described in the literature, and a case definition has also been proposed for this condition. The exact etiology is unknown and exclusion of infectious, metabolic, autoimmune and toxin mediated injuries is essential. Management for this condition is supportive, but some may require liver transplantation. Infection prevention and control practices are important as the etiology remains unidentified.Copyright © 2023, Indian Academy of Pediatrics.

Evaluation with Roc Analysis, Logistics Regression Analysis and Other Statistical Tests Analysis of Retrospective Results of Biochemistry Laboratory Results, Analysised in Covid-19 Infected Serum or Plasma (Crp, Procalcitonin, Ferritin, D-Dimer, Fibrinogen, Ast, Alt, Ldh)

Objectives: A new type of coronavirus that emerged in Wuhan, China at the end of 2019, caused the Covid-19 (SARS-COV2) pandemic. Common cold symptoms are seen, but in more severe cases, pneumonia, Acute Respiratory Distress Syndrome (ARDS), coagulopathy, multi-organ failure are seen, and it causes death in the course of time. In this study, among the laboratory parameters followed in cases diagnosed with Covid-19 and followed in home isolation, service and intensive care unit;It is aimed to retrospectively evaluate CRP, procalcitonin, ferritin, D-Dimer, fibrinogen AST, ALT and LDH levels with ROC and other statistical analyzes in terms of predicting mortality in the treatment and follow-up of the disease. Materials-Methods: Between 01.04.2020 and 01.10.2020, the patients who applied to Necmettin Erbakan University Meram Medical Faculty Hospital with cold symptoms and were diagnosed with Covid-19 with RT-PCR positivity, were analyzed from Covid-19 infected serum and plasma. The results of the biomarkers were examined. Demographic data, vital signs and laboratory findings of the cases were compared. The results were statistically evaluated with the SPSS 22.0 package program. Result(s): 300 cases who received home isolation, service and supportive treatment in the intensive care unit were included in the study. Crp, Pct, D-dimer, ferritin, fibrinogen, LDH, AST and ALT values were found to be statistically significant. According to the results of ROC (Receiver Operating Characteristic) analysis performed to determine the predictive values of laboratory parameters that were significant as a result of univariate statistical analysis, Crp (0.890775), Pct (0.86795), D-dimer (0.856975), ferritin (0.836975), LDH (0.7829), fibrinogen (0.773925), AST (0.685925) and ALT (0.594025) were found. Conclusion(s): The high mutation ability of SARS-CoV-2 makes it difficult to control the pandemic. Therefore, early diagnosis of the disease has gained importance for the treatment of patients with high mortality risk. According to the ROC results we obtained in this study, it supports that CRP, Procalcitonin, Ferritin, D-dimer and LDH levels can be used as effective parameters in determining the prognosis and mortality risk in Covid-19 patients.

A Guide to Mental Health in Family Under the COVID-19 Epidemic

This book tells us from a professional perspective how to deal with stress response in the family, effectively address family problems in the epidemic, and handle the infectious emotions. This book is a profound explanation of the new stress, conflicts, and problems arising at home amid the epidemic. It provides people with a psychological self-help scale to effectively distinguish the normal and abnormal states of psychological response. Besides, it also provides professional psychological assistance and suggestions for special groups, including children, the elderly, the quarantined, and the bereaved, in order to help all families actively respond to the epidemic with the power of psychology. © Beijing Normal University Press 2022.

Multiple Cerebral Infarcts Triggered by Sars-Cov-2 Virus in an Asymptomatic Cadasil Patient: Case Report

During the coronavirus pandemic, increasing evidence has confirmed that the SARS-CoV-2 virus is susceptible to increased risk of stroke. On the other hand, the relationship between the SARS-CoV-2 virus and CADASIL was among the topics discussed in the literature with a small number of cases. In this case report, we present multiple cerebral infarcts in an asymptomatic CADASIL patient and we aim to shed light on the complex nature of cerebrovascular manifestations of the SARS-CoV-2 virus. A 50-year-old man with an unremarkable past medical history was admitted to our department with fever and neurologic manifestations on the 6th day of self-isolation due to positive reverse-transcriptase-polymerasechain-reaction assay in a nasopharyngeal sample for SARS-CoV-2. Neurological deficits were related to the acute vascular lesions located in the border-zone areas of both hemispheres, corpus callosum, and cerebellar peduncles on brain MRI. Lesions in chronic nature in the bilateral subcortical white matter predominantly involving the external capsule and temporal poles were also challenging. As a result of a comprehensive study that could explain the neurological status and imaging findings, the CADASIL diagnosis is reached by genetic testing for NOTCH-3. The experience, in this case, suggests considering patients with suspicious MRI findings for CADASIL diagnosis during the coronavirus pandemic. Further studies are needed to explain the underlying pathophysiological mechanisms related to cerebrovascular manifestations of SARS-CoV-2.Copyright © 2022 by Turkish Cerebrovascular Diseases Society.

Containing an Island: Coronavirus (Covid-19) Outbreak in Perhentian Islands, Terengganu State of Malaysia, in 2021

Background: The spread of COVID-19 was inevitable and has not spared small and isolated communities, including the community on Perhentian Island in Besut District, Terengganu. Managing clusters in small islands can be difficult, given the limited resources. This study explores the characteristics of COVID-19 cases and the experience of outbreak containment at Perhentian Island. Methodology: A retrospective study involving record review of COVID-19 cases and at-risk individuals registered under the Perhentian Cluster were retrieved from the Besut District Health Office COVID-19 online registry from the 16th August 2021 until 6th October 2021. All notified cases and close contacts who fulfilled the inclusion criteria were extracted and analysed using descriptive statistics. Result(s): A total of 1,093 out of 2,500 community members of Perhentian Island were screened of which 170 (15.5%) tested positive for COVID-19, while 923 (84.5%) tested negative. Among individuals who tested positive, the majority were adults (52.4%), males (51.8%), Malays (98.8%), and villagers (96.5%). Clinical characteristics were categorized into: asymptomatic (55.9%), had no known medical comorbidities (90.6%), low-risk groups (87.1%), vaccinated (57.6%), and admitted to PKRC (97.1%) for treatment. Multiple agencies were involved in the outbreak containment of the Perhentian Cluster, working collectively and in good coordination. Conclusion(s): The outbreak was attributed to community gatherings and close interactions among villagers. Prompt actions, targeted planning, and inter-agency collaboration were the key factors in successful containment of further spread of COVID-19 in Perhentian Island.Copyright © 2023, Faculty of Medicine, University of Malaya. All rights reserved.

The role of motivational interviewing training in supporting the practice of COVID-19 contact tracers

Purpose: To explore how motivational interviewing (MI) training might benefit the practice of COVID-19 contact tracers. Design/methodology/approach: Following co-production of a MI training package, with a United Kingdom (UK) track and trace organisation, training was delivered virtually to 101 volunteer participants involved in contact tracing. Data were captured via an online survey, incorporating questions from recognised measures of occupational self-efficacy and workplace wellbeing, prior to the training. Open data fields were used to gather feedback about participants' reasons for attending, and views about the training afterwards. Finding(s): Although the contact tracers reported high occupational self-efficacy and workplace wellbeing, both quantitative and qualitative data suggested participants saw practitioner value and utility in MI. Research limitations/implications: The sample was self-selecting and typically involved contact tracers from UK local authorities. The study did not measure impact on compliance with self-isolation guidance and/or providing details of contacts, and larger-scale research would be needed to establish this. This was not a pre-post-test evaluation study, and measures of occupational self-efficacy and workplace wellbeing were gathered to give insight into the sample and to test the feasibility of using this survey for a future large-scale study. The research was conducted during the height of the pandemic. While UK COVID-19 contact tracing services have since been reduced, there are potential implications for infection control more generally. Practical implications: MI is potentially a useful approach for enhancing contact tracing practice. However, implementation factors should be carefully considered, to ensure effective and sustainable practice. Social implications: Improved practice in contact tracing could have potential benefits in infection control, through improving compliance with central guidance, although this requires more widespread investigation. Originality/value: This is the first empirical study to investigate how MI training could benefit COVID-19 contact tracing practice.Copyright © 2023, Emerald Publishing Limited.

Clinical and laboratory characteristics of the COVID-19 disease in adult patients

BACKGROUND: In December 2019, a new coronavirus, SARS-CoV-2, appeared in Wuhan, China. This virus is the cause of the COVID-19 disease. This infection later spread to the whole world. The goal of this article is to present the clinical and laboratory characteristics of patients with COVID-19 treated in the Faculty Hospital Pilsen. METHOD(S): In this monocentric, retrospective study, clinical and biochemical data of 89 adult patients with COVID-19 was analyzed. These patients were in the care of the Faculty Hospital Pilsen between March 14 and April 7. RESULT(S): In this cohort, made up of 89 patients, 63 were treated as outpatients and 26 were hospitalized. 10 patients required intensive care. The most common symptoms among patients were cough and fever. Dyspnea was present in 29 patients. A CT scan showed bilateral pneumonia in 23 of the admitted patients. Fever and bilateral pneumonia were significantly more common in patients >= 60 years old (p=0.047, and p=0.001, respectively). Of lab results, the patients in intensive care had significantly higher values of C-reactive protein, procalcitonin, lactate dehydrogenase, interleukin 6, myoglobin and ferritin. CONCLUSION(S): The most common symptoms of COVID-19 are fever and cough. These two symptoms are simultaneously present in more than half the cases. Approximately 1/10th of patients requires intensive care. Higher values of lactate dehydrogenase, myoglobin and ferritin on patient admission appear to be a strong predictive factor of the patient's status progressing into requiring ICU attention.Copyright © 2020 Neuroendocrinology Letters

Impact on Human Mental Behavior after Pass through a Long Time Home Quarantine Using Machine Learning

In the present situation, COVID-19 is a very common and dangerous issue in the whole world. Ensuring our healthy mental state is very essential at the period of COVID-19. But as a result of being in the home quarantine for a long time, people are going to notice a mental change such as stress, depression, mood swing. We proposed an RHMCD model which helps us to reach our required goal. This model contains machine learning algorithms. We examined our work with Naive Bayes classifiers, Support Vector Machine, and logistic regression. For gaining the report of mental conditions we used the sentiment analysis technique. For measuring the level of depression we also used a decision tree approach.

Socio-Demographic Depletion Due to COVID-19 Impact and Government Intervention: A Review in Bangladesh

COVID-19 known as coronavirus disease, has been dominating the headlines all over the world since about a year ago which is now almost under control. The World Health Organization (WHO) has labeled it a pandemic. Bangladesh is struggling with this virus with its scarce resources. Nearly two million people have been reported as confirmed cases of coronavirus disease in 185 countries worldwide in the five months after the virus first emerged in December 2019. The COVID-19 pandemic affected people directly or indirectly all over the world. There has been a slowdown in all sectors worldwide and most of the global population was placed under lockdown. The families of 43.9 percent of the students might live in poverty, and export revenues from RMG fell by 18.12% from the previous year. Households in Chittagong city corporation experienced the least decrease in average income (11.7%) while the households in Sylhet city corporation experienced the most reduction in average income (63.4%). This COVID-19 created a widespread global shock. The government of Bangladesh has declared several stimulus plans worth a combined total of about USD 11.90 billion for the agricultural sector to ensure the country's food and nutritional security, for doctors, nurses, and the homeless for social safety, and for business sectors including small and medium enterprises and cottage industries at the early age of pandemic. There were 23 COVID-19 stimulus packages total across the nation, with a total outlay of USD 1.23 billion which is 4.44% of GDP. Approximately USD 3,529 million for the service sector and the impacted industries, USD 589 million to cover workers' salaries/allowances, and those of staff working in industries focused on exports were allocated as a package to tackle the serious impact of the COVID-19 pandemic.Copyright © 2023, Science Publications. All rights reserved.

A business retrieval model using scenario planning and analytics for life during and after the pandemic crisis

The COVID-19 pandemic crisis has fundamentally changed the way we live and work forever. The business sector is forecasting and formulating different scenarios associated with the impact of the pandemic on its employees, customers, and suppliers. Various business retrieval models are under construction to cope with life after the COVID-19 Pandemic Crisis. However, the proposed plans and scenarios are static and cannot address the dynamic pandemic changes worldwide. They also have not considered the peripheral in-between scenarios to propel the shifting paradigm of businesses from the existing condition to the new one. Furthermore, the scenario drivers in the current studies are generally centered on the economic aspects of the pandemic with little attention to the social facets. This study aims to fill this gap by proposing scenario planning and analytics to study the impact of the Coronavirus pandemic on large-scale information technology-led Companies. The primary and peripheral scenarios are constructed based on a balanced set of business continuity and employee health drivers. Practical action plans are formulated for each scenario to devise plausible responses. Finally, a damage management framework is developed to cope with the mental disorders of the employees amid the disease.Copyright © 2021 The Author(s)

Awareness and implications of COVID-19 Omicron variant in patients with Parkinson's disease and their caregivers: A crosssectional study

Objective: SARS-CoV-2 (COVID-19) omicron variant emerged as the third wave of concern for the entire world. In this study, we aimed to study the level of the understanding, awareness and perception of Parkinson's disease (PD) patients and their caregivers (CG) regarding the Omicron variant of COVID-19 disease using a self-reported survey questionnaire. Background(s): The Omicron variant of SARS-CoV-2 was reported after almost 2 years of COVID-19 emergence. Attempts to control COVID-19 infection have resulted in countries being placed under lockdown, with a focus on self-isolation. These factors have complicated the situation of patients with serious chronic conditions like Parkinson's disease, which are dependent on their caregivers and doctors for their checkups, activities of daily living and and drug administrations & dose adjustments. Further patients of PD with cognitive impairment, are particularly vulnerable to these social restrictions and potential loss of access to usual support systems. Method(s): We conducted a prospective study using a structured questionnaire involving patients with Parkinson's disease who visited and following treatment in our outpatient department of Neurology before and during the COVID-19 pandemic. Research was conducted from February 2022 to August 2022. Result(s): A total of 134 patients with the disease and 114 caregivers were assessed. Approximately, 4.5% of the patients and 1.8% of the CG got infected with Omicron-Covid 19. Almost 77% of the patients and CG were having knowledge about the omicron variant but nearly half (59.7%) of them did now knew the symptoms. Approximately, 95% of the patients did not experienced worsening of their symptoms after Covid vaccination. Majority of patients (95.5%) and their CG (98.2%) neither got any symptoms suggestive of Omicron, nor opted for testing. Approximately, 95% of patients opted physical medicine as preferable choice for consultation, and accuracy of assessment and treatment/ medicines were the reasons behind. Conclusion(s): Omicron variant came and went unknown to many people. According to the current observations from this study, no strong relation between the Covid vaccination, pandemic, omicron variant infection and symptoms of PD could be established. Further research on large number of patients should be planned and executed.

Impacting factors and sources of perceived stress by home-quarantined residents in Shanghai during COVID-19 epidemic.

BACKGROUND: Home-quarantine is one of the most common measures implemented to prevent or minimize the transmission of COVID-19 among communities. This study assessed stress levels of the home-quarantined residents in Shanghai during a massive wave of COVID-19 epidemic this year, explored the stress sources perceived by the respondents, and analyzed the association between each of the sociodemographic factors and the stress level. METHODS: This online survey was launched during April 23 - 30, 2022, the early stage of a massive wave of COVID-19 in Shanghai, China. Participants were quarantined-residents negative for COVID-19. They were asked to list some situations that were their major concerns and perceived stressful, in addition to sociodemographic and COVID-19 related information. Moreover, they were asked to complete the Perceived Stress Scale-14 (PSS-14) for the assessment of stress level. RESULTS: A total of 488 valid questionnaires were collected from 192 male and 296 female respondents. Overall, 207 persons (42.42%) presented high stress level (PSS-14 score ≥43). The top three concerns perceived stressful by respondents are "not allowed to go outdoors", "uncertain duration of the epidemic", and "lack of food supply". Fewer than 50% of the respondents perceived the other situations stressful. Higher proportions of young adults (≤ 29 years old), males, unemployed, singles, and those with low income (≤ 1999 yuan/month) perceived high stress compared to their counterparts, none of COVID-19 related factors is associated with the stress level, including location of residence, result of nucleic acid test, knowledge about COVID-19, whether vaccinated, and quarantine duration. CONCLUSION: Home-quarantine applied to people negative for COVID-19 led to a lot of major concerns that may be perceived stressful, whereas the virus-related factors did not show significant impact on mental health of the respondents.

Risk factors for pandemic-related workplace absenteeism among health care workers and the impact of vaccination

Background: Staff absences due to illness or quarantine as result of the SARS-CoV-2 pandemic or vaccinationrelated adverse events are known. We examined their numbers in health care workers (HCW) from pulmonary hospitals in Germany. Method(s): A study-specific online questionnaire was created to assess individual experiences and the impact of the pandemic. From December 1 to 23, 2022 staff from all occupational groups at 7 pulmonary hospitals were surveyed. Result(s): A total of 1136 HCW participated, 75% being female, 92.6% having received at least one vaccine dose at the time of the survey, 65.2% three, and 108 reporting a previous SARS-CoV-2 infection. Of HCW with positive PCR test, 98% reported home quarantine, with a quarantine period of median (range) 14 (1-52) days, while of those without positive PCR test, 11.3% reported quarantine over 14 (1-25) days. In addition, 23.5% of HCW reported absences due to vaccination effects over 2 (1-21) days. Overall, 37% (n=420) of HCW reported pandemic-related absences (median 5 days), with 3523 cumulative days of absence from work, among them 2826 related to illness or quarantine, and 697 to vaccination effects. Independent risk factors for pandemic-related absences of more than 5 days included COVID-19 illness (p<0.001) and not having been vaccinated at the time of the interview (OR 2.6;95%CI: 1.2-5.6;p= 0.009). Sex, age, or working in direct patient care or risk areas were not relevant. Conclusion(s): In HCW from German pulmonary hospitals, the average total days of absenteeism from work related to SARS-CoV-2 were about 3 days per participant, and vaccination-associated absenteeism contributed about one fifth to this number.